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KMID : 0363220060440121464
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Korean Journal of Dermatology
2006 Volume.44 No. 12 p.1464 ~ p.1466
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A Case of Nicolau Syndrome Treated by Surgical Excision
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Ku Bon-Seok
Lee Yeong-Kyu
Kwon Oh-Eon
Lee Chae-Wook
Kim Ki-Ho
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Abstract
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Nicolau syndrome or embolia cutis medicamentosa is an acute necrotic condition of skin that follows intramuscular injection of drugs. A 36-year-old man developed a painful, purpuric and erythematous patch on his left buttock following an intramuscular injection of diclofenac sodium. Histologically, the patch lesion displayed epidermal necrosis, dermal degeneration, and vascular thrombosis. We report a rare case of Nicolau syndrome following intramuscular injection of diclofenac sodium. In our case, the patient was successfully treated by surgical excision with primary closure.
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KEYWORD
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Diclofenac sodium, Embolia cutis medicamentosa, Nicolau Syndrome
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